Zulkifli Mohamed Amin studied music in LASALLE-SIA college of the arts and joined the Orkestra Melayu Singapura (OMS) as a trombone player and since then, doubled up as a keyboardist and accordionist. He has been a music director and band leader for various performances and festivals.

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He was appointed as the conductor and leader of SYMO since 2010. His active involvement and enthusiasm for the development of the orchestra has gained him due respect from musicians to bring music to a new frontier.

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Having mostly self-taught in composition since a tender age of 13, Zulkifli has participated in composition master classes by world renowned composers which include, Professor Gerald Brophy (Australia), Zachar Laskewicz (Austria), Eric James Watson (United Kingdom) as his composition tutor, Dr. Alan Laurens (America) as his conducting professor, and Dr. Alex Dea (indonesia) in Ethnomusicology.

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Since 2003, Zulkifli has been actively involved in conducting and music directorship. This led him to the formation of his contemporary pop orchestra for a concert at Lasalle-SIA which is also his conducting debut and in 2006, appointed as Music Director of the closing concert of Singapore Management University Arts Festival 2006 among others. In 2013, he was appointed as the Music Director for Semara Seni in collaboration with Sri Warisan Performing Arts.

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He has been an active pit musician throughout his musical journey having played in dance productions. The start of 2004-05, Zulkifli begin his new focus on world music and visual-art music composition and performance. Although busy with commissioned works and projects, Zulkifli is an ardent researcher with interest in cross-cultural music composition techniques, ethnomusicology; south-east Asia region in particular and world music performance and composition.

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Currently, Zulkifli is an arts educator and with the emphasis of developing young talents who are passionate in the arts. He is also a musician with the Asian Contemporary Ensemble (ACE).

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Zulkifli also serves as the Artistic Director of Nusantara Arts.